Students in the SEA-PHAGES program headed up by Pitt biologist Graham Hatfully identifying and naming thousands of bacteriophages - viruses that attack bacteria, while CRC powers the sequencing and analysis of a sliver of the billions-plus-strong, everchanging populaton of bacteriophages. “Bacteria and phages are locked in a 3-billion year war,” Hatfull says simply. “Dynamic populations have been evolving for a long time, and they keep evolving.”
Left, phages armed for battle. Image by Travis Mavrich in the Hatfull lab.
Students step into science by identifying and naming thousands of bacteriophages - viruses that attack bacteria - as part of the SEA-PHAGES program headed up by Pitt biologist Graham Hatfull. CRC powers the sequencing and analysis of a sliver of the billions-plus-strong, everchanging populaton of bacteriophages. “Bacteria and phages are locked in a 3-billion year war,” Hatfull says simply. “Dynamic populations have been evolving for a long time, and they keep evolving.”
Left, Pitt students Aishwarya Mukundan and Daniel Zipfel hunt for phages in Pitt's SEA-PHAGE lab.
Are human rights around the world improving? It’s a big question. Have decades of attention from governments and non-governmental organizations such as Amnesty International had any effect? Pitt political science professor Michael Colaresi sought to answer that question by analyzing language in U.S. State Department human rights reports using a machine learning model powered by Pitt CRC to parse millions of words of text, a task which otherwise would require countless human hours.
Spaces filled up fast for Pitt CRC's annual cluster training workshop. Due to that demand, we've added a third session of the workshop to go over new hardware, modules, and queuing system, as well as strategies around queuing, scratch space; exit codes.Time and location is:
Congratulations to Pitt CRC's own Karl Johnson for a groundbreaking paper ilustrating a long-sought explanation of the molecular-level creation of the indispensable polymer polyisobutylene (PIB). Johnson, William Kepler Whiteford Professor in the Swanson School’s Department of Chemical & Petroleum Engineering and associate director of Pitt CRC, was PI on the project funded by the Ohio-based Lubrizol Corporation.
Left: a simulated reaction mechanism of a proton transfer from a catalyst to isobutylene, the first step in the process of PIB becoming a ploymer. (Minh Nguyen Vo/Johnson Research Group).
With CRC support, James Pipas and Paul Cantalupo analyze virus genomes found in mosquitoes - and in the blood meal mosquitoes draw from their prey. The mosquitoes are located, trapped, and identified using advanced drones and robotic traps in Texas, the Caribbean island of Grenada, and Tanzania. It is all part of Project Premonition, a global effort led by Microsoft Research to identify existing and emerging viruses.
CRC high-performance computing resources enhance the productivity of Pitt researchers - and help improve teaching. Pitt CRC research faculty consultants serve as a resource for faculty members to explore new methods to enrich student learning while preparing them for careers.
"Teaching and learning enhance CRC’s computing research mission. We play a role in helping grow the research community from the ground up."
- Barry Moore II, PhD
Research Assistant Professor
Center for Research Computing