When not working with CRC collaborators, research assistant professor Barry Moore ll spends evenings teaching himself advanced programming languages like the functional programming language Haskell - while streams his own learning sessions. Barry and his audience learn together. Follow the live stream and find previous sessions on his Twitch channel and find an archive of sessions on his YouTube channel. In the future, he plans to work with other functional programming languages such as Purescript. Happy computing!
Ruth Mostern, director of Pitt’s World History Center, spearheads the World Historical Gazetteer digital atlas supported by CRC. The WHG is searchable by names of places and natural features covering several thousand years, with data in multiple layers from sources linking people and events associated with places. “The gazetteer is a two-way platform for scholarly communication,” explains Mostern. “It will improve people’s own research while researchers also contribute to a growing shared resource.”
At left is the skyline of modern Istanbul, Turkey, identified in the WHG by the city's many names in different languages, and associated historical events over millennia.
Xiaosong Wang, associate professor in pathology and biomedical Informatics, leads the Computational Genomics and Translational Cancer Biology lab in the Pitt Cancer Institute. This unified computational and wet laboratory explores cancer genomics using next generation sequencing and genome profiling in a multidisciplinary approach uniting researchers in bioinformatics, genetics, and molecular and cell biology. The lab’s guiding principle is translational “bench to bedside” research – transforming genomic data into precision medicine to battle cancers, particularly breast cancer.
CRC is supporting the development and human imaging studies of a powerful new MRI technology being done by Pitt's Radiofrequency Research Facility and the 7 Tesla Bioengineering Research program led by bioengineering professor Tamer Ibrahim. The 7 Tesla scanner is one of the most powerful MRI devices in the world, able to reveal details not visible in typical MRI machines. particularly in brain markers implicated in diseases associated with aging, such as Alzheimer’s and late life depression, The lab l develops adiofrequency antennas to create even electromagnetic waves to avoid potentially dangerous heating of brain tissue, for which the team uses CRC to simulate hundreds of thousands of possible antenna configurations.
The star-nosed mole of North America and the naked mole rat of East Africa are both blind. They underwent the same adapatation to living underground, although they are different species separated by thousands of miles. Marine mammals like manatees and dolphins underwent shared adaptations to aquatic life. What could the convergence of independent physical changes reveal about the evolution of the genes responsible for those physical changes? The labs of Maria Chikina and Nathan Clark explore this evolution relying on CRC resources for computation tasks to compare rates of evolution for a gene in one species to rates of evolution for a gene in another species.
In the spring of 1006 CE a supernova in the constellation Lupus was the brightest stellar object ever recorded on Earth, bright enough for several months to be easily visible in daylight. Most supernovae are not dramatically visible from Earth and don’t leave visible evidence. What they do leave are supernova remnants: expanding balls of gas heated to millions of degrees Celsius. The remnants hold clues to the origins and deaths of stars, and the lab of Pitt astrophysicist Carles Badenes searches for those clues helped by the resources of the Center for Research Computing.